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Kurwanya abantu IGFBP-1 Antibody, Imbeba Monoclonal

Ibisobanuro bigufi:

Kwezwa Ubusabane-chromatografiya Isotype /
Ubwoko bwakiriwe Imbeba Ubwoko Umuntu
Gusaba Chemiluminescent Immunoassay (CLIA) / Immunochromatography (IC)

Ibicuruzwa birambuye

Ibicuruzwa

Ibisobanuro birambuye

Amakuru rusange
IGFBP1, izwi kandi nka IGFBP-1 hamwe na insuline imeze nkikura-ihuza poroteyine 1, ni umwe mu bagize umuryango wa insuline umeze nk’imikurire ihuza umuryango wa poroteyine.IGF ihuza poroteyine (IGFBPs) ni poroteyine za 24 kugeza 45 kDa.IGFBPs zose uko ari esheshatu zisangiye 50% homology kandi zifite aho zihurira na IGF-I na IGF-II muburyo bumwe nkubunini bwa ligande kuri IGF-IR.Intungamubiri za poroteyine za IGF zongerera igice cya kabiri cyubuzima bwa IGF kandi byagaragaye ko zibuza cyangwa zitera ingaruka ziterambere ry’iterambere rya IGF ku muco w’akagari.Bahindura imikoranire ya IGFs hamwe na selile yakira.IGFBP1 ifite indangarugero ya IGFBP hamwe na thyroglobulin ubwoko-I.Ihuza ibintu byombi bikura nka insuline (IGFs) I na II kandi bizenguruka muri plasma.Guhuza iyi poroteyine byongerera igice cya kabiri cyubuzima bwa IGFs kandi bigahindura imikoranire yabyo hamwe nubutaka bwakirwa.

Ibyiza

Icyifuzo CLIA (Gufata-Kumenya):
4H6-2 ~ 4C2-3
4H6-2 ~ 2H11-1
Isuku > 95% nkuko byagenwe na SDS-PAGE.
Buffer 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4
Ububiko Ubike mubihe bidasanzwe kuri -20 ℃ kugeza -80 ℃ umaze kwakira.
Saba kugabanya poroteyine muke kugirango ubike neza.

Kugereranya Kurushanwa

Bioantibody Indwara Yasuzumwe Igiteranyo
Ibyiza Ibibi
Ibyiza 35 0 35
Ibibi 1 87 88
Igiteranyo 36 87 123
Umwihariko 100%
Ibyiyumvo 97%

Tegeka amakuru

izina RY'IGICURUZWA Injangwe.Oya Indangamuntu ya Clone
IGFBP-1 AB0028-1 4H6-2
AB0028-2 4C2-3
AB0028-3 2H11-1
AB0028-4 3G12-11

Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.

Imirongo

1.Rutanen EM.Gukura kwa insuline kumera gukura poroteyine 1: US 1996.

2.Harman, S, Mitchell, n'abandi.Urwego rwa Serumu ya Insuline-Nkura yo Gukura I (IGF-I), IGF-II, IGF-Binding Protein-3, na Antigen yihariye ya Prostate nk'abahanuzi ba Kanseri ya Prostate Clinique [J].Ikinyamakuru cya Clinical Endocrinology & Metabolism, 2000.


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