Kurwanya abantu PLGF Antibody, Imbeba Monoclonal
Ibisobanuro birambuye
Amakuru rusange
Preeclampsia (PE) nikibazo gikomeye cyo gutwita kirangwa na hypertension na proteinuria nyuma yibyumweru 20 byo gutwita.Preeclampsia ibaho muri 3‑5% yo gutwita kandi bikavamo impfu nyinshi z'ababyeyi n'ababyeyi cyangwa impinja cyangwa impinja.Kugaragara kwa Clinical birashobora gutandukana muburyo bworoheje kandi bukomeye;preeclampsia iracyari imwe mu mpamvu zitera uburwayi bw'inda n'inda.
Preeclampsia isa nkaho iterwa no kurekura ibintu bya angiogeneque biva mumyanya itera imikorere mibi ya endoteliyale.Urwego rwa serumu ya PlGF (ibintu bikura byimyanya myanya) na sFlt - 1 (fms soluble - nka tyrosine kinase - 1, bizwi kandi ko byakira VEGF reseptor - 1) bihinduka mubagore barwaye preeclampsia.Byongeye kandi, uruzinduko rwa PlGF na sFlt - 1 rushobora gutandukanya gutwita bisanzwe na preeclampsia na mbere yuko ibimenyetso byindwara bibaho.Mugihe cyo gutwita bisanzwe, ibintu bya - angiogenic PlGF byiyongera mugihembwe cya mbere kandi bikagabanuka uko gutwita bigenda byiyongera.Ibinyuranye, urwego rwibintu birwanya antiogeneque sFlt - 1 biguma bihamye mugihe cyambere cyo hagati no hagati yo gutwita kandi bikiyongera kugeza igihe.Mu bagore barwaye preeclampsia, sFlt - 1 byagaragaye ko ari hejuru naho urwego rwa PlGF rwaragaragaye ko ruri munsi ugereranije no gutwita bisanzwe.
Ibyiza
| Icyifuzo | CLIA (Gufata-Kumenya): 7G1-2 ~ 5D9-3 5D9-3 ~ 7G1-2 |
| Isuku | > 95% nkuko byagenwe na SDS-PAGE. |
| Buffer | PBS, pH7.4. |
| Ububiko | Ubike mubihe bidasanzwe kuri -20 ℃ kugeza -80 ℃ umaze kwakira. Saba kugabanya poroteyine muke kugirango ubike neza. |
Kugereranya Kurushanwa
Tegeka amakuru
| izina RY'IGICURUZWA | Injangwe.Oya | Indangamuntu ya Clone |
| PLGF | AB0036-1 | 7G1-2 |
| AB0036-2 | 5D9-3 | |
| AB0036-3 | 5G7-1 |
Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.
Imirongo
1.Yamamaye MA, Lindheimer MD, de Swiet M, n'abandi.Gutondekanya no gusuzuma indwara ya hypertension yibibazo byo gutwita: itangazo ryatanzwe na societe mpuzamahanga ishinzwe kwiga hypertension mugutwita (ISSHP).Inda ya Hypertens 2001; 20 (1): IX-XIV.
2.Uzan J, Carbonnel M, Piconne O, nibindi.Mbere ya eclampsia: pathophysiology, gusuzuma, no kuyobora.Vasc Health Risk Manag 2011; 7: 467-474.
