Antibody irwanya abantu, Imbeba Monoclonal

Amakuru rusange
Pepsinogen I, ibanziriza pepsin, ikorwa na mucosa gastrica hanyuma ikarekurwa muri gastric lumen no kuzenguruka kwa peripheri.Pepsinogen igizwe numuyoboro umwe wa polypeptide wa acide 375 amine ifite uburemere bwa molekile ya 42 kD.PG I (isoenzyme 1-5) isohorwa cyane cyane na selile nkuru muri mucosa fundic, mugihe PG II (isoenzyme 6-7) isohorwa na glande pyloric na mucosa yegeranye na duodenal.
Precursor yerekana umubare w'utugingo ngengabuzima two mu gifu kimwe na selile glandular, kandi ikurikirana gastric atrophy mu buryo butaziguye.Barahagaze kandi bidasanzwe kuko bakora akazi kabo mubihe bibi biboneka muri sisitemu yo kurya.Atrophy ya corpus mucosa itera synthesis nkeya ya pepsinogen I bityo ikarekura muke muri serumu.Serumu pepsinogen I yerekana imikorere n'imiterere ya mucosa gastric.