Kurwanya abantu s100 β Antibody, Imbeba Monoclonal
Ibisobanuro birambuye
Amakuru rusange
S100B ni calcium ihuza poroteyine, isohoka muri astrocytes.Ni poroteyine ntoya ya dimeric cytosolike (21 kDa) igizwe na ββ cyangwa αβ iminyururu.S100B igira uruhare mubikorwa bitandukanye byimikorere idasanzwe.
Mu myaka icumi ishize, S100B yagaragaye nkumukandida wa periferique biomarker yamaraso - inzitizi yubwonko (BBB) no gukomeretsa CNS.Urwego rwo hejuru rwa S100B rugaragaza neza ko hariho imiterere ya neuropathologique harimo gukomeretsa umutwe hamwe nindwara zifata ubwonko.Urwego rusanzwe rwa S100B ukuyemo rwose gukuramo CNS yingenzi.Serum S100B nayo yavuzwe nkikimenyetso cyingirakamaro mugutahura hakiri kare metastase ya melanoma nibibazo byubwonko biterwa no gukomeretsa mumutwe, kubaga umutima, hamwe nubwonko bukabije.
Ibyiza
| Icyifuzo | CLIA (Gufata-Kumenya): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
| Isuku | > 95% nkuko byagenwe na SDS-PAGE. |
| Buffer | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
| Ububiko | Ubike mubihe bidasanzwe kuri -20 ℃ kugeza -80 ℃ umaze kwakira. Saba kugabanya poroteyine muke kugirango ubike neza. |
Kugereranya Kurushanwa
Tegeka amakuru
| izina RY'IGICURUZWA | Injangwe.Oya | Indangamuntu ya Clone |
| s100 β | AB0061-1 | 5H2-3 |
| AB0061-2 | 22G7-5 | |
| AB0061-3 | 21A6-1 |
Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.
Imirongo
1. Ostendorp T, Leclerc E, Galichet A, nibindi.Ubushishozi nuburyo bukora mubikorwa bya RAGE na multimeric S100B [J].Ikinyamakuru EMBO, 2007, 26 (16): 3868-3878.
2. R, D, Rothoerl, n'abandi.Serumu nyinshi S100B kurwego rwabarwayi bafite ihahamuka badakomeretse mumutwe.Kubaga Neuroshirurgie, 2001.
