Kurwanya abantu MMP-3 Antibody, Imbeba Monoclonal
Ibisobanuro birambuye
Amakuru rusange
Matrix metallopeptidase 3 (mu magambo ahinnye yitwa MMP3) izwi kandi nka stromelysin 1 na progelatinase.MMP3 ni umwe mu bagize umuryango wa matrix metalloproteinase (MMP) abanyamuryango bagize uruhare mu gusenya matrice idasanzwe mu mikorere isanzwe ya physiologiya, nko gukura kwa emboro, kubyara, kuvugurura ingirabuzimafatizo, hamwe n'indwara zirimo arthrite na metastasis.Nkibanga rya zinc-biterwa na endopeptidase, MMP3 ikora imirimo yayo cyane cyane muri matrise idasanzwe.Iyi poroteyine ikorwa na inhibitori ebyiri zikomeye: alpha2-macroglobuline na tissue inhibitor za metalloprotease (TIMPs).MMP3 igira uruhare runini mugutesha agaciro ubwoko bwa kolagen II, III, IV, IX, na X, proteoglycans, fibronectin, laminine, na elastine.Na none, MMP3 irashobora gukora izindi MMP nka MMP1, MMP7, na MMP9, bigatuma MMP3 ikomeye muguhindura ingirabuzimafatizo.Kudakwirakwiza MMP byagize uruhare mu ndwara nyinshi zirimo arthrite, ibisebe bidakira, encephalomyelitis, na kanseri.Inzitizi ya synthique cyangwa naturel ya MMPs itera kubuza metastasis, mugihe kugenzura MMPs byatumye kanseri yibasira cyane.
Ibyiza
| Icyifuzo | CLIA (Gufata-Kumenya): 11G11-6 ~ 8A3-9 11G11-6 ~ 5B9-4 |
| Isuku | > 95%, bigenwa na SDS-PAGE |
| Buffer | PBS, pH7.4. |
| Ububiko | Ubike mubihe bidasanzwe kuri -20 ℃ kugeza -80 ℃ umaze kwakira. Saba kugabanya poroteyine muke kugirango ubike neza. |
Kugereranya Kurushanwa
Tegeka amakuru
| izina RY'IGICURUZWA | Injangwe.Oya | Indangamuntu ya Clone |
| MMP-3 | AB0025-1 | 11G11-6 |
| AB0025-2 | 8A3-9 | |
| AB0025-3 | 5B9-4 |
Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.
Imirongo
1.Yamanaka H, Matsuda Y, Tanaka M, n'abandi.Serum matrix metalloproteinase 3 nkumuhanuzi wurwego rwo kurimbuka hamwe mumezi atandatu nyuma yo gupimwa, kubarwayi barwaye rubagimpande ya rubagimpande [J].Arthrits & Rheumatism, 2000, 43 (4): 852–858.
2.Hattori Y, Kida D, Kaneko A.Urwego rusanzwe rwa matrix metalloproteinase-3 rushobora gukoreshwa mu guhanura ivuriro n’imikorere isanzwe ku barwayi barwaye rubagimpande ya rubagimpande [J].Indwara ya rubagimpande, 2018.
