Anti-muntu Her2 Antibody, Imbeba Monoclonal

Amakuru rusange
Ikura ryibyorezo byumuntu 2 (HER2), bizwi kandi nka ErbB2, NEU, na CD340, ni ubwoko bwa I membrane glycoprotein kandi ni mubwoko bwikura ryibyorezo (EGF).Poroteyine ya HER2 ntishobora guhuza ibintu bikura bitewe no kubura ligand ihuza domaine yayo kandi ikabuza kwikora.Nyamara, HER2 ikora heterodimer hamwe nabandi bagize umuryango wa EGF yakira ligande, bityo rero igahuza ligand kandi ikongerera imbaraga za kinase-ihuza ibikorwa bya molekile zo hepfo.HER2 igira uruhare runini mugutezimbere, gukwirakwiza selile no gutandukana.Bivugwa ko HER2 gene ifitanye isano no kurwara nabi ndetse no kutamenya neza kanseri nyinshi, zirimo amabere, prostate, intanga ngore, kanseri y'ibihaha n'ibindi.