Amakuru rusange
Poroteyine ya Retinol ihuza (4)Nkumunyamuryango wa lipocalin birenze urugero, RBP4 irimo structure bar-ingunguru ifite umwobo usobanuwe neza isohoka mu mwijima, hanyuma ikanatanga retinol mu bubiko bwumwijima kugeza ku nyama za peripheri.Muri plasma, uruganda RBP4-retinol ikorana na transthyretine (TTR), kandi uku guhuza ni ngombwa mu gukumira RBP4 gusohoka binyuze mu mpyiko glomeruli.RBP4 yerekanwe kumasoko ya ectopique itanga retinol mumaso, kandi kubura kwayo bigira ingaruka kumyerekano ya nijoro.Vuba aha, RBP4 nka adipokine, usanga igaragarira mubice bya adipose kandi bifitanye isano n'umubyibuho ukabije, kurwanya insuline (IR) na diyabete yo mu bwoko bwa 2 (T2DM).
Icyifuzo | CLIA (Gufata-Kumenya): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
Isuku | > 95% nkuko byagenwe na SDS-PAGE. |
Buffer | PBS, pH7.4. |
Ububiko | Ubike mubihe bidasanzwe kuri -20 ℃ kugeza -80 ℃ umaze kwakira. Saba kugabanya poroteyine muke kugirango ubike neza. |
izina RY'IGICURUZWA | Injangwe.Oya | Indangamuntu ya Clone |
RBP4 | AB0032-1 | 9D11-8 |
AB0032-2 | 3C8-1 | |
AB0032-3 | 3D4-1 | |
AB0032-4 | 1C6-1 |
Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.
1.Aiwei YB, Vijayalakshmi V, Bodles AM, n'abandi.Retinol ihuza poroteyine 4 imvugo mu bantu: isano yo kurwanya insuline, gutwika, no gusubiza pioglitazone. [J]J Clin Endocrinol Metab (7): 2590-2597.
2.Umuyobozi mukuru, Karin S, Gerhard P, n'abandi.Poroteyine ya serumu retinol ihuza 4 igabanuka nyuma yo kugabanuka ibiro mubintu bifite umubyibuho ukabije. [J].Ikinyamakuru cya Clinical Endocrinology & Metabolism (3): 1168-71.