Kurwanya abantu SHBG Antibody, Imbeba Monoclonal

Amakuru rusange
Imisemburo yimibonano mpuzabitsina ihuza globuline (SHBG) ni glycoproteine ​​ya kDa hafi 80-100;ifitanye isano cyane na hormone 17 beta-hydroxysteroid nka testosterone na estradiol.SHBG
kwibanda muri plasma bigengwa nibindi bintu, androgene / estrogene iringaniye, imisemburo ya tiroyide, insuline nibintu byokurya.Nibintu byingenzi byingenzi byo gutwara poroteyine kuri estrogene na andorogene mu maraso ya peripheri.Kwishyira hamwe kwa SHBG nikintu gikomeye kigenga ikwirakwizwa ryayo hagati ya poroteyine na leta zubuntu.Plasma SHBG yibanze ni
yibasiwe n'indwara nyinshi zitandukanye, indangagaciro zo hejuru ziboneka muri hyperthyroidism, hypogonadism, androgen sensensitivite na cirrhose ya hepatike kubagabo.Imyitwarire mike iboneka muri myxoedema, hyperprolactinaemia na syndromes yibikorwa bikabije bya androgene.Gupima SHBG ni ingirakamaro mugusuzuma ibibazo byoroheje bya metabolisme ya androgene kandi bigafasha kumenya abo bagore bafite hirsutism bakunze kwitabira kuvura estrogene.