Amakuru rusange
Alpha-fetoprotein (AFP) ishyirwa mubanyamuryango ba gene ya alubumuide igizwe na albumin, AFP, vitamine D (Gc), na alpha-albumin.AFP ni glycoproteine ya 591 aside amine hamwe na karubone ya hydrata.AFP ni imwe muri poroteyine zihariye zihariye kandi ni poroteyine yiganje mu buzima bwa mbere bwo gusama kwa muntu nk'ukwezi kumwe, iyo albumin na transferrin biboneka ku rugero ruto.Irabanza ikomatanyirizwa mumuntu numufuka wumuhondo numwijima (amezi 1-2) hanyuma biganjemo umwijima.Umubare muto wa AFP ukorwa na GI tract yigitekerezo cyabantu.Byaragaragaye ko AFP ishobora kongera kugaragara muri serumu ku bwinshi mu buzima bwabantu bakuru ifatanije nuburyo busanzwe bwo gusubiza ibintu hamwe no gukura nabi.Alpha-fetoprotein (AFP) ni ikimenyetso cyihariye cya kanseri ya hepatocellular (HCC), teratoblastoma, hamwe nudukoko twa neural tube (NTD).
Icyifuzo | CLIA (Gufata-Kumenya): 3C8-6 ~ 11D1-2 8A3-7 ~ 11D1-2 |
Isuku | > 95%, bigenwa na SDS-PAGE |
Buffer | PBS, pH7.4. |
Ububiko | Ubike mubihe bidasanzwe kuri -20℃kugeza -80℃amaze kwakira. Saba kugabanya poroteyine muke kugirango ubike neza. |
izina RY'IGICURUZWA | Injangwe.Oya | Indangamuntu ya Clone |
AFP | AB0069-1 | 11D1-2 |
AB0069-2 | 3C8-6 | |
AB0069-3 | 8A3-7 |
Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.
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2.Tomasi igituntu, nibindi.(1977) Imiterere n'imikorere ya Alpha-Fetoprotein.Isubiramo rya buri mwaka ry'ubuvuzi.28: 453-65.
3.Leguy MC, n'abandi.(2011) Isuzuma rya AFP mumazi ya amniotic: kugereranya tekinike eshatu zikoresha.Ann Biol Clin.69 (4): 441-6.