Amakuru rusange
MPO (myeloperoxidase) ni enzyme ya peroxidase isohorwa na leukocytes ikora igira uruhare runini mu ndwara zifata umutima, cyane cyane mugutangiza imikorere mibi ya endoteliyale.Myeloperoxidase (MPO) ni enzyme y'ingenzi, ikaba ari kimwe mu bigize sisitemu ya antibacterial muri neutrophile na monocytes.MPO igira uruhare mu gusubiza umuriro ahantu henshi mu mubiri, harimo na glande y’inyamabere.Myeloperoxidase (MPO), enzyme yihariye ya polymorphonuclear leukocyte, yakoreshejwe mbere mu kubara umubare wa neutrophile mu ngingo.Igikorwa cya MPO wasangaga gifitanye isano n'umubare w'utugingo ngengabuzima twa neutrophil.Sisitemu ya MPO igira uruhare runini muguhashya kwandura no gusiba selile mbi.Nubwo bimeze bityo, guhinduranya muri sisitemu ya MPO birashobora gutuma ADN yangirika na kanseri.Polymorphism muri gen MPO yajyanye no kwiyongera kwa MPO hamwe n’impanuka nyinshi zo kwandura kanseri.Myeloperoxidase (MPO) ni imwe mu ntego nyamukuru za antigene ya antineutrophil cytoplasmic autoantibodies (ANCA) iboneka ku barwayi bafite vasculitis yo mu mitsi mito na Pauci-immune nekrotizing glomerulonephritis.Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) ni autoantibody ikunze kuboneka ku barwayi bafite vasculitide.
Icyifuzo | CLIA (Gufata-Kumenya): 4D12-3 ~ 2C1-8 4C16-1 ~ 2C1-8 |
Isuku | > 95%, bigenwa na SDS-PAGE |
Buffer | PBS, pH7.4. |
Ububiko | Ubike mubihe bidasanzwe kuri -20 ℃ kugeza -80 ℃ umaze kwakira. Saba kugabanya poroteyine muke kugirango ubike neza. |
izina RY'IGICURUZWA | Injangwe.Oya | Indangamuntu ya Clone |
MPO | AB0007-1 | 2C1-8 |
AB0007-2 | 4D12-3 | |
AB0007-3 | 4C16-1 |
Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.
1.Klebanoff, S. J.Myeloperoxidase: inshuti n'umwanzi [J].J Leukoc Biol, 2005, 77 (5): 598-625.
2.Baldus, S. Myeloperoxidase Urwego rwa Serumu Ihanura ibyago ku barwayi bafite Syndromes ikaze ya Coronary [J].Kuzenguruka, 2003, 108 (12): 1440.