Amakuru rusange
Gukura-gutandukanya ibintu 15 (GDF15), bizwi kandi nka MIC-1, ni umunyamuryango wibanga wibintu bikura bikura (TGF) -β birenze urugero, nkikintu gishya kirwanya antihypertrophique mumutima.GDF-15 / GDF15 ntigaragarira mumutima usanzwe ukuze ahubwo iterwa no gusubiza ibibazo bitera hypertrophyie hamwe na cardiomyopathie yagutse kandi bigaragarira cyane mu mwijima.GDF-15 / GDF15 ifite uruhare mukugenzura inzira yumuriro na apoptotique mumyanya yakomeretse no mugihe cyindwara.GDF-15.GDF-15 / GDF15 gukabya gukabije biva mu gice cyagutse cya erythroide bigira uruhare mu kurenza fer muri syndromes ya thalassemia muguhagarika imvugo ya hepcidine.
Icyifuzo | CLIA (Gufata-Kumenya): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
Isuku | > 95%, bigenwa na SDS-PAGE |
Buffer | PBS, pH7.4. |
Ububiko | Ubike mubihe bidasanzwe kuri -20 ℃ kugeza -80 ℃ umaze kwakira. Saba kugabanya poroteyine muke kugirango ubike neza. |
izina RY'IGICURUZWA | Injangwe.Oya | Indangamuntu ya Clone |
GDF-15 | AB0038-1 | 3A2-1 |
AB0038-2 | 23F1-5 | |
AB0038-3 | 6C1-9 | |
AB0038-4 | 4D5-8 |
Icyitonderwa: Bioantibody irashobora kugereranya ingano kubyo ukeneye.
1.Wollert KC, Kempf T, Peter T, n'abandi.Agaciro Kumenyekanisha Gukura-Itandukaniro-15 mu barwayi bafite Syndrome ya Non-ST-Hejuru Ikomeye ya Coronary [J].Kuzenguruka, 2007, 115 (8): 962-971.
2.Kempf T, Haehling SV, Peter T, n'abandi.Ikoreshwa ryingirakamaro ryo gutandukanya ibintu-15 kubarwayi bafite ikibazo cyumutima udakira. [J]Ikinyamakuru cyo muri Amerika College of Cardiology, 2007, 50 (11): 1054-1060.