Virusi ya Monkeypox yihuta

Virusi ya Monkeypox yihuta,
ikizamini cya monospot vs ebv serology monospot ikizamini ebv monkeypox america ikizamini cya virusi ya monkeypox nigute wapima virusi ya powassan hari ikizamini cya virusi ya varicella zoster virusi ya mosaic virusi ibimenyetso bya monkeypox,

Amakuru rusange

Bioantibody yambere-mubyiciro-by-ibyiciro-byiza-byateguwe kugirango ikemure ibikenewe byubuvuzi bidakenewe binyuze mu guteza imbere imiti ivura mono na bi-yihariye, imiti ya antibody hamwe na macrophage ikangura abarwayi ku isi yose.

Amateka

Ubuvumbuzi bwavumbuwe bwa tekinoroji ya monoclonal antibody (mAb) na Kohler na Milstein mu 1975 byatanze amahirwe yo gukora antibodi nk'icyiciro cyo kuvura (Kohler & Milstein, 1975).Antibodiyite za Monoclonal (mAbs) ni imwe mu miti ikoreshwa cyane mu ndwara zandura cyangwa kuvura kanseri kuko zihitamo kwibasira indwara ziterwa na virusi, selile zandura, selile kanseri, ndetse na selile selile.Muri ubu buryo, bahuza kurandura molekile hamwe ningirabuzimafatizo zifite ingaruka nke ugereranije nubundi buryo bwo kuvura.By'umwihariko, kanseri ivura kanseri mAbs irashobora kumenya poroteyine zo hejuru-selile kuri selile hanyuma ikica selile igenewe hakoreshejwe uburyo bwinshi.
Kuba umuntu bigabanya cyane ubudahangarwa bwa antibody yo kuvura abantu, bigatuma ubuyobozi budakira bushoboka.Iterambere nk'iryo mu buhanga bwa antibody ryatumye habaho guturika mugutezimbere imiti mAbs mu myaka icumi ishize.Urukurikirane rw'ibikomoka kuri antibody, birimo poroteyine za Fc-fusion, antibody-ibiyobyabwenge bya conjugate (ADCs), immunocytokine (antibody-cytokine fusions), hamwe na antibody-enzyme fusion, nabyo byatejwe imbere kandi bigacuruzwa nk'ubuvuzi bushya.

Ingaruka zibiyobyabwenge

Ku barwayi, imiti mishya igamije gusobanura ingaruka nkeya, ibitaro bike, kuzamura imibereho, kongera umusaruro, kandi cyane, ubuzima bwagutse.Ariko iterambere ryibiyobyabwenge ninzira ndende, igoye.

Reba

Kohler G, Milstein C. Imico ikomeza ya selile yahujwe isohora antibody yibintu byateganijwe mbere.Kamere.1975; 256: 495–497.doi: 10.1038 / 256495a0
Ecker DM, Jones SD, Levine HL.Isoko ryo kuvura antibody ya monoclonal.MAbs.2015; 7: 9–14.doi: 10.4161 / 19420862.2015.989042.
Peters C, Brown S. Antibody-ibiyobyabwenge bifata nkibintu bishya birwanya kanseri ya chimiotherapeutics.Biosci Rep. 2015; 35 (4): e00225.Yatangajwe 2015 Jul 14. Iraboneka kuri https://pubmed.ncbi.nlm.nih.gov/26182432/.Byemewe muri Nyakanga 2020.
Reichert, JM, na Valge-Archer, VE (2007).Iterambere ryiterambere rya monoclonal antibody kanseri ivura.Nat Rev Ibiyobyabwenge Discov 6, 349–356.
Lazar, GA, Dang, W., Karki, S., Vafa, O., Peng, JS, Hyun, L., Chan, C., Chung, HS, Eivazi, A., Yoder, SC, n'abandi.(2006).Antibody yakozwe na Fc ihindagurika hamwe nibikorwa byongerewe imbaraga.PNAS 103, 4005–4010.

Virusi ya Monkeypox ni filovirus itera indwara yandura cyane izwi nka monkeypox.Irashobora kuboneka mubihugu byinshi bya Afrika, nubwo byavuzwe no muri Amerika no mubindi bihugu byu Burayi.

Ibimenyetso bya monkeypox harimo umuriro, kubabara umutwe, kubabara imitsi, kubabara umugongo, kubyimba lymph node, isesemi no kuruka.Igisebe gitangirira mumaso kandi kigakwirakwiza umubiri kumaboko n'amaguru, mubisanzwe bigenda bishira nyuma yibyumweru bitatu.

Ni ngombwa kumenya ko iyi ndwara idafite ikigega cy’inyamaswa;imanza zose zagiye ziva mubantu kugeza kubantu.